High Purity Dl-Dithiothreitol Raw Material CAS 3483-12-3 Low Price for You
| Product Name |
High Purity Dl-Dithiothreitol Raw Material CAS 3483-12-3 Low Price for You |
| Appearance |
White Powder |
| Test Method |
HPLC |
| MOQ |
1000gram |
| Shelf Life |
24 months under cool and dry storage condition |
| Shipping Service |
FEDEX, TNT, DHL, UPS Express (door to door service) by air with smooth and safe customs clearance |
What is Dl-Dithiothreitol Powder ?
Pharmaceutical Dl-Dithiothreitol Raw Material CAS 3483-12-3 Dl-Dithiothreitol Powder
Dithiothreitol is a commonly used reducing agent, also known as dimercaptothreitol (DTT for short). It has strong reducing property, which is largely due to the conformational stability of its oxidation state six-membered ring (containing disulfide bond). Reducing power is affected by pH value and can only play a reducing role when pH value is greater than 7. This is because only the deprotonated mercaptan anion (-S --) is reactive, mercaptan (-SH) is not; The pKa of sulfhydryl group is generally ~ 8.3.
Application of Dl-Dithiothreitol Powder : Dithiothreitol has antioxidant effect, which can protect the reducing groups on the enzyme molecules, maintain the reducing environment, and stabilize the activity of the enzyme. DTT also contains RNA enzyme inhibitors, which can inhibit the activity of RNA enzyme. It has similar effects to mercaptoethanol (dimercaptoethanol), but the pungent odor of DTT is much less and the toxicity is much less than mercaptoethanol. In addition, when the concentration of DTT is 7 times lower than that of mercaptoethanol, the two effects are similar. But the DTT price is slightly higher. Cleavage and sequence analysis of protein disulfide bond used as protein Euclidean protector.
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