CAS No.: | 104987-11-3 |
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Formula: | C44h69no12 |
EINECS: | 1308068-626-2 |
Type: | Pharmaceutical Intermediates |
Appearance: | Powder |
Quality: | Refined |
Samples: |
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Customization: |
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Product Name | Highest Purity 99% Tacrolimus Powder CAS 104987-11-3 China Tacrolimus |
CAS | 104987-11-3 |
Appearance | White fine powder |
MF | C44H69NO12 |
MW | N/A |
Assay | 99% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
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What is Tacrolimus ?
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
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