Function: | Hormones and Regulation of Endocrine Function of Drug, Vitamins and Minerals Deficiency Drug, Antineoplastic, Antibiotic and Antimicrobial Agents, Antiparasitic, Antipyretic Analgesic and Non-Steroidal Anti-Inflammatory Analgesic, Itraconazole |
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Certification: | GMP |
Grade Standard: | Medicine Grade |
Type: | Analysis reagent |
State: | White Powder |
Volatile: | Not Volatile |
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Product name | Competitive Price Itraconazole Powder CAS 84625-61-6 Raw Material Purity Bulk Itraconazole |
Appearance | white Powder |
Cas | 84625-61-6 |
Assay | 99% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Itraconazole is a triazole antifungal agent. It inhibits the fungal CYP(cytochrome P450) oxidase-mediated synthesis of ergosterol. Itraconazole also acts as an effective hedgehog signaling inhibitor in a Ptch-independent manner, presumably by binding smoothened (Smo) at a site distinct from that targeted by cyclopamine and SAG. Itraconazole is an inhibitor of CYP3A4. 1) Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus which fluconazole is not. 2) It is also prescribed for systemic infections, such as aspergillosis, candidiasis, and cryptococcosis 3) Itraconazole has also recently been explored as an anticancer agent for patients with basal cell carcinoma. |
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