CAS No.: | 134523-03-8 |
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Formula: | C66h68caf2n4o10 |
EINECS: | 200-659-6 |
Type: | Synthesis Material Intermediates |
Appearance: | Liquid |
Quality: | Industrial |
Samples: |
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Customization: |
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Product Name | Pharmaceutical Raw Material Powder CAS 134523-03-8 Atorvastatin Calcium |
CAS | 134523-03-8 |
Assay | 99%min, 98.0% --101.0% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Atorvastatin Calcium ? CAS: 134523-03-8 MF: C66H68CaF2N4O10 MW: 1155.36 EINECS: 200-659-6 Melting point: 176-178°C Storage temp.: Store at +4°C Appearance: White Crystalline Powder |
Lipitor was launched in Canada, the Netherlands, the UK and the US as an orally-active hypocholesterolemic agent.
It was the first pharmaceutical product ever to attain over one billion dollars in sales in its first year. It can be
synthesized by a number of routes but the most efficient involves the Paal-Knorr reaction of an acetonide protected
dihydroxy amino ester and a diaryl phenylacetamide diketone. Lipitor is a liver selective, reversible competitive
inhibitor of HMG-CoA reductase, the rate limiting step in cholesterol biosynthesis. Lipitor monotherapy resulted
in a reduction of LDL cholesterol by up to 60%. Lipitor is about 2-4 times more potent, on a dosage basis, than
Simvastatin.
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