Wholesale Pharma Raw Powder Nisoldipine CAS 63675-72-9 Used in Antihypertensive
| Product Name |
Wholesale Pharma Raw Powder Nisoldipine CAS 63675-72-9 Used in Antihypertensive |
| CAS |
63675-72-9 |
| Appearance |
Light Yellow Powder |
| Molecular formula |
C20H24N2O6 |
| Molecular Weight |
388.41 |
| Assay |
98% |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
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What is Nisoldipine ?
Nisoldipine, nimodipine, nicardipine and Nirendipine are four kinds of dihydropyridine calcium antagonists commonly used at present. Calcium antagonists, also known as calcium blockers, slow channel blockers and calcium channel blockers, belong to antiarrhythmic drugs and are the general name of a class of drugs that inhibit the activation of calcium ion channels and reduce calcium ion flow. In 1985 the International Cardiology Association recommended a uniform term for "calcium antagonists". The discovery and application of calcium antagonists is one of the most important advances in cardiovascular therapy in the late 20th century, and has been widely used in the treatment of angina pectoris, myocardial infarction, hypertension, heart failure and arrhythmia.
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Fuction And Application of Nisoldipine
,Nisoldipine, also known as niphenipropyl, deshintine, nierxin, Yili, Nierli and Diyixin, is the strongest calcium antagonist at
present. It was first developed and successfully by Bayer Pharmaceutical in Germany. It is highly selective to vascular smooth
muscle and its activity to blood vessels is 3-5 times that of other tissues, which can significantly reduce peripheral vascular
resistance and myocardial oxygen consumption, and increase coronary blood flow. Improve perfusion in ischemic area, improve
myocardial tolerance to ischemia, and significantly reduce the proportion of myocardial necrosis in low-perfusion area due to
coronary artery occlusion. At the same time, dilate peripheral arteries, reduce peripheral resistance and cardiac afterload, increase
cardiac output and cardiac index, relieve coronary spasm, improve left ventricular function, prevent fatal ventricular fibrillation,
and have obvious and lasting antihypertensive effect. Minimal effect on heart rate and myocardial contractility. The dilatation of
coronary artery was 4 ~ 10 times stronger than nifedipine. It is a highly effective and low toxic drug for prevention and treatment
of acute myocardial ischemia and hypertension.
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Package:
2. Shipping Advise:
1. By Express
------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.
2. By Air
------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.
3. By sea
------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.
1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
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