Manufacturer Supply CAS 5579-84-0 Apis Raw Materials Powder Betahistine Dihydrochloride

• CAS No.: 5579-84-0
• Formula: C8h14cl2n2
• EINECS: 226-966-5
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: HRK-Betahistine dihydrochloride
• Colour: White
• Product Name: Betahistine Dihydrochloride Powder
• Test: HPLC
• Mf: C8h14cl2n2
• CAS: 5579-84-0
• MW: 209.12
• Active Ingredient: Betahistine Dihydrochloride
• Sample: Betahistine Dihydrochloride Avaliable
• Certificate: GMP ISO USP Bp
• Assay: 90% Min
• Grade Standard: Medicine Grade
• Application: Vertinary Raw Materials
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min Betahistine Dihydrochloride
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

                   
Manufacturer Supply CAS 5579-84-0 Apis Raw Materials Powder Betahistine Dihydrochloride

Product Name	Betahistine Dihydrochloride powder CAS 5579-84-0
CAS	5579-84-0
Appearance	White Powder
Molecular formula	C8H14Cl2N2
Molecular Weight	209.12
Assay	98%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Betahistine dihydrochloride? Betahistine dihydrochloride is a histamine H3 receptors inhibitor used as an antivertigo drug. Target: Histamine Receptor Betahistine dihydrochloride, a structural analogue of histamine with weak histamine H(1) receptor agonist and more potent H(3) receptor antagonist properties. Betahistine dihydrochloride acts centrally by enhancing histamine synthesis within tuberomammillary nuclei of the posterior hypothalamus and histamine release within vestibular nuclei through antagonism of H(3) autoreceptors [1]. Therapeutic effects of betahistine in vestibular disorders result from its antagonist properties at histamine H(3) receptors (H(3)Rs). On inhibition of cAMP formation and [(3)H]arachidonic acid release, betahistine behaved as a nanomolar inverse agonist and a micromolar agonist. After acute oral administration, Betahistine increased t-MeHA levels with an ED(50) of 2 mg/kg, a rightward shift probably caused by almost complete first-pass metabolism. Therapeutic effects of betahistine result from an enhancement of histamine neuron activity induced by inverse agonism at H(3) autoreceptors [2].

Fuction And  Application of  Betahistine dihydrochloride

Betatine hydrochloride treatment of inner ear vertigo (ie, Meniere's syndrome), cerebral arteriosclerosis, cerebral
insufficiency and hypertension caused by dizziness, vomiting and tinnitus.

 
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Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

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