| Function: | Hormones and Regulation of Endocrine Function of Drug, Antibiotic and Antimicrobial Agents, Antiparasitic, Original Drug Resistant Microbes, Omeprazole |
|---|---|
| Certification: | GMP, Reach, FDA, Omeprazole |
| Grade Standard: | Omeprazole |
| Type: | Analysis reagent |
| State: | Omeprazole |
| Volatile: | Not Volatile |
| Samples: |
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| Customization: |
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Audited Supplier 
GMP Certifiate Factory Supply Omeprazole Powder CAS 73590-58-6 Purity Bulk Omeprazole
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Product Name
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GMP Certifiate Factory Supply Omeprazole Powder CAS 73590-58-6 Purity Bulk Omeprazole |
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Appearance
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White powder
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Assay
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99%min |
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Test
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HPLC
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Certificate
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ISO 9001
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CAS
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73590-58-6 |
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MF
|
C17H19N3O3S |
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Storage Temperature
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Cool Dry Place
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Product Description OF Omeprazole omeprazole (omeprazole) is a proton pump inhibitor used to treat diseases such as peptic ulcer and gastroesophageal reflux disease (GERD). It can act specifically on the site of the proton pump in gastric parietial cells, and is converted into the active form of sulfamide, and then irreversely binds to the sulfhydryl group of the proton pump through disulfide bonds. The formation of a complex of sulfamide and proton pump (H+-K+ -ATPase), thereby inhibiting the activity of this enzyme, so that H+ in parietal cells cannot be transported to the stomach cavity, blocking the last step of gastric acid secretion, which can greatly reduce the amount of gastric acid in gastric juice. |
Function and Application OF Omeprazole
Therefore, this product has a strong and lasting inhibitory effect on gastric acid secretion caused by various
causes (such as basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin
and vagus stimulation, including the gastric acid secretion caused by dibutyl cyclic adenylate that cannot be
inhibited by H2 receptor blocking drugs). This is related to the irreversibility of the inhibition effect of this
product on the proton pump, and the effect of acid secretion can be restored only after the formation of a
new proton pump.
Omeprazole is a kind of proton pump inhibitor that can effectively inhibit the secretion of gastric acid.
The product names circulating on the market include ameprazole, omirazole, subflumidazole, losec,
methoxysulfonazole, woprazole, and womiprazole, which belong to the class of acid suppressive drugs.
Other common acid suppressive drugs include Pantoprazole, Rabeprazole, and esomeprazole. The
mechanism of action is to selectively act on the parietal cells of the gastric mucosa, inhibit the activity of
H+,K+ -ATPase on the secretory microtubules formed by the apical membrane of the parietal cells of the
gastric mucosa and the tubular vesicles in the cytoplasm, thus effectively inhibiting the secretion of gastric
acid, with rapid effect, which is suitable for the treatment of gastric ulcer, duodenal ulcer, reflux esophagitis
and gastrinoma (Zuo-Ai syndrome).
However, it should be noted that overuse of acid suppressive drugs such as omeprazole can lead to a
decrease in the concentration of stomach acid and weaken the acidity, so that the bacteria entering the
stomach may not be killed, and enter the intestine, doubling the risk of intestinal infection, and then diarrhea
may be possible. Due to the reduced stomach acid affect digestion, and then affect the intestinal absorption
of calcium, iron and other trace elements and vitamins, resulting in calcium deficiency in the body, prone to
fracture.
GMP Certifiate Factory Supply Omeprazole Powder CAS 73590-58-6 Purity Bulk Omeprazole
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