China Manufacturer Loratadine Powder CAS 100643-71-8 Pharmaceutical Chemicals Loratadine

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: 99%
• Model NO.: HRK-Loratadine
• Product Name: Loratadine
• Certificate: GMP ISO USP Bp
• Assay: 99% Min Loratadine
• Test: HPLC
• Mf: C22h23cln2o2
• MW: 382.88
• Active Ingredient: Loratadine
• Sample: Loratadine Avaliable
• Grade Standard: Medicine Grade
• Application: Human API
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Colour: White
• MOQ: 1kg
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

   

Product name	China Manufacturer Loratadine Powder CAS 100643-71-8 Pharmaceutical Chemicals Loratadine
Color	WHITE Powder
Assay	99%
CAS	79794-75-5
MW	382.88
MF	C22H23ClN2O2
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

What is Loratadine ? Loratadine is a commonly used anti-allergy drug, which belongs to the second generation of long-acting tricyclic antihistamines. It acts quickly, has strong effect, does not contain hormones, and is metabolized into more active desloratadine after absorption by the human body. It competitively inhibits histamine H1 receptor and inhibits allergic symptoms caused by histamine, without obvious anticholine and central inhibitory effects. It is used clinically to relieve symptoms associated with allergic rhinitis, such as sneezing, runny nose and itchy nose, as well as itching and burning of the eyes. It is also used to relieve the symptoms of chronic urticaria and other allergic skin diseases.

Application of Loratadine

Antihistamines are highly selective to the peripheral nerve H1 receptor, have strong effects and a long time.
For abnormal arthritis, allergic rhinitis. The national Class II anti-allergy drug is used to relieve nasal and
non-nasal symptoms of seasonal allergic rhinitis and relieve chronic urticaria

Function of Loratadine

Common adverse reactions include headache, drowsiness, fatigue, dry mouth, blurred vision, decreased or
increased blood pressure, palpitations, syncope, hyperkinetic activity, changes in liver function, jaundice,
hepatitis, liver necrosis, hair loss, seizures, breast enlargement, erythema multiforme, and systemic anaphyl
axis. Drug interaction: Drugs that inhibit the function of liver drug metabolizing enzymes can slow down the
metabolism of this product, such as itraconazole and ketoconazole. Taking 400mg ketoconazole daily can
increase the plasma concentration of this product and its active metabolite decarboxethylloratadine, but no
electrocardiogram changes were observed. Combined with macrolide antibiotics, cimetidine, theophylline
and other drugs can also inhibit the metabolism of loratadine.

2. rapid onset, persistent efficacy of loratadine itself has activity, good absorption, onset time of less than 30min. After oral
administration, the maximum plasma concentration was about 3h, and the Cmax was 3.98 ng / mL-1 at a single dose of
H-1, and the clearance rate was from 114 to 201L. A study of clinical onset time in patients with allergic rhinitis as the
object of proof, desloratadine than antihistamine effect existing faster, the average onset time of 28.45min, and 1H of
desloratadine and mizolastine, cetirizine is 2h. Half life is about 24h, and the effect is lasting..

 

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Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

why choose us ?
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