• High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
  • High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
  • High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
  • High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
  • High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
  • High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

CAS No.: 78628-80-5
Formula: C21h26cln
EINECS: 616-640-4
Type: Pharmaceutical Intermediates
Appearance: Powder
Quality: Refined
Samples:
US$ 100/kg 1 kg(Min.Order)
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Customization:
Diamond Member Since 2019

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Basic Info.

Model NO.
HRK-Terbinafine Hydrochloride
Colour
White
Product Name
Terbinafine Hydrochloride Powder
Test
HPLC
Mf
C21h26cin
CAS
78628-80-5
MW
327.89
Active Ingredient
Terbinafine Hydrochloride
Sample
Terbinafine Hydrochloride Avaliable
Certificate
GMP ISO USP Bp
Assay
90% Min
Grade Standard
Medicine Grade
Application
API Raw Materials
Type of Product
Auxiliaries and Other Medicinal Chemicals
Storage
Cool Dry Place
Shelf Life
2 Years Proper Storage
Factory
GMP Standard
Transport Package
1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
Specification
99% min Terbinafine Hydrochloride
Trademark
Henrikang
Origin
Shaanxi China
Production Capacity
500000kg/Year

Product Description

                   High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective
Terbinafine
Product Name Hot sale API Terbinafine hydrochloride
CAS 78628-80-5
Appearance White crystalline powder
Molecular formula C21H26CIN
Molecular Weight 327.89
Assay 98%
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location
 
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine


 
What is Terbinafine hydrochloride?
 
Terbinafine hydrochloride 78628-80-5 a synthetic antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues.
Terbinafine·HCl 78628-80-5 a member of the class of antifungals, has been found to be a specific inhibitor of ergosterol synthesis via squalene epoxidase inhibition. 
Squalene epoxidase is an enzyme released by the dermatophyte fungi to break down Squalene, which interferes with cell membrane function and wall synthesis.
Additionally, Terbinafine 78628-80-5 has also been reported to suppress cell proliferation in vitro and in vivo through inhibition of DNA synthesis and apoptosis activation. It has also been noted that by pretreating of cells with a p21 specific antisense oligonucleotide the Terbinafine induced inhibition of cell growth can be reversed.


Function of Terbinafine hydrochloride

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in and , soluble in ethanol,
and slightly soluble in water. Like other , terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase,
an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion
ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability,
causing fungal cell lysis.


Application of Terbinafine hydrochloride


1. Terbinafine hydrochloride is mainly effective on the dermatophyte group of fungi.

2. As a 1% cream or powder, Terbinafine hydrochloride is used topically for superficial skin infections such as
jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream
works in about half the time required by other antifungals.

3. Oral 250mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by
a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which
topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity,
so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have
been studied.

4.Terbinafine HCLmay induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus
erythematosus should first discuss possible risks with their doctor before initiation of therapy.

High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
Company Information
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine


Our Certificate
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

Our Service
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

Our Research
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

why choose us ?
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine
High Purity API Material Terbinafine Hydrochloride Powder CAS 78628-80-5 Anti-Infective Terbinafine

 

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