Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, HSE, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Solid |
Purity: | 99% |
Samples: |
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Customization: |
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Product name |
GMP Factory Supply Osimertinib Mesylate Powder CAS 1421373-66-1 Raw Materials Osimertinib Mesylate |
Appearance | White Powder |
Cas |
1421373-66-1 |
Assay | 99% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Osimertinib Mesylate ?
Osimertinib (previously known as mereletinib or AZD9291) is a third-generation epidermal receptor tyrosine kinase inhibitor drug.
AZD9291 is a Kinase Inhibitor. The mechanism of action of osimertinib is as a Kinase Inhibitor, and Cytochrome P450 3A Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 1A2 Inducer, and Breast Cancer Resistance Protein Inhibitor. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR. |
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Function of Osimertinib Mesylate
AZD9291 used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). Osimertinib is associated with a moderate rate of serum aminotransferase elevations during therapy and rare instances of clinically apparent acute liver injury.
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