Pharmaceutical Chemical Isrib (trans-isoMer) Isrib-Trans-Isrib Powder CAS 1597403-47-8 Transisomer

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >98%
• Model NO.: HRK-ISRIB(trans-isoMer)
• Product Name: Isrib(Trans-Isomer)
• Appearance: White Powder
• Active Ingredient: Isrib(Trans-Isomer)
• Sample: Isrib(Trans-Isomer) Avaliable
• Einecs No: 0
• CAS No: 1597403-47-8
• Mf: C22h24cl2n2o4
• Model Number: Hrk-Isrib(Trans-Isomer)
• Certificate: GMP ISO USP Bp
• Test: HPLC
• Grade Standard: Medicine Grade,Cosmetic Grade
• Type of Product: Brain Health
• Assay: 99.9% Min
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Transport Package: 100g Per Bag
• Specification: 99% min
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 5000kg/Year

Product Description

Pharmaceutical Chemical ISRIB(trans-isoMer) ISRIB-trans-ISRIB Powder CAS 1597403-47-8
Transisomer

Product name	Pharmaceutical Chemical ISRIB(trans-isoMer) ISRIB-trans-ISRIB Powder CAS 1597403-47-8 Transisomer
Appearance	White powder
Assay	99%min
Test	HPLC
Certificate	ISO 9001
CAS	1597403-47-8
MF	C22H24Cl2N2O4
Storage Temperature	Cool Dry Place

What is ISRIB(trans-isoMer) ? ISRIB(Trans-ISomer), the trans ISRIB, is a highly selective PERK inhibitor with an IC50 of 5 nM. In vitro studies, ISRIB inhibited the expression of endogenous ATF4, while the expression of XBP1smRNA splinter and XBP1s remained unchanged. ISRIB inhibits endoplasmic reticulum balance by inhibiting estrogen receptor balance and the PERK signaling pathway, reducing the survival rate of cells faced with endoplasmic reticulum stress.

Application of ISRIB(trans-isoMer)

ISRIB has good characteristics in pharmacokinetic experiments and has good bioavailability in organisms. Intraperitoneally injected (0.25 mg/kg) ISRIB in mice increased long-term memory by enhancing spatial memory and fear memory.

Function of ISRIB(trans-isoMer)

ISRIB has good characteristics in pharmacokinetic experiments and has good bioavailability in organisms. Intraperitoneally injected (0.25 mg/kg) ISRIB in mice increased long-term memory by enhancing spatial memory and fear memory.

Pharmaceutical Chemical ISRIB(trans-isoMer) ISRIB-trans-ISRIB Powder CAS 1597403-47-8 Transisomer    
ISRIB(trans-isoMer);ISRIB(trans-isoMer) Powder;ISRIB-trans-ISRIB
ISRIB(trans-isoMer)
CAS:1597403-47-8