Factory Supply White Powder Purity Azithromycin Powder CAS 83905-01-5
Antibiotic Azithromycin
| Product name |
Factory Supply White Powder Purity Azithromycin Powder CAS 83905-01-5 Antibiotic Azithromycin |
| Appearance |
white Powder |
| Cas |
83905-01-5 |
| Assay |
99% |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
An Introduction to Azithromycin :
Azithromycin is a kind of antibiotic drug widely used in clinic. It has the advantages of broad antibacterial spectrum, little irritation to the gastrointestinal tract, fast oral absorption and so on. It is used by both adults and children. Azithromycin is one of the most commonly used antibiotics in the clinical treatment of bacterial infection-related diseases due to its smaller side effects than cephalosporin antibiotics. Azithromycin is a second-generation semi-synthetic derivative of macrolides, which is different from erythromycin in structure. A methyl substituted nitrogen is inserted into the 9a site of erythromycin lactone ring. So you have a 15-membered macrolide.
Application and Function of Azithromycin :
Azithromycin's mechanism of action is similar to erythromycin. It plays an antibacterial role by binding to the 50S subunit of the ribosomes of sensitive bacteria, which inhibits RNA dependent protein synthesis and retains the antibacterial profile of typical erythromycin. The activity against chlamydia was similar to erythromycin. Compared with erythromycin, the antibacterial activity against gram-negative bacteria was significantly improved. The antibacterial activity against influenza bacillus and Neisseria gonorrhoeae was more than 4 times stronger than erythromycin, the antibacterial activity against Legionella was about 2 times stronger than erythromycin, and the antibacterial activity against enterobacteriaceae was also significantly stronger than erythromycin. MIC for most gram-negative bacteria is less than 1μg/ml. Staphylococcus aureus and Streptococcus pyogenes were cross-resistant to erythromycin. It also has good killing effect on toxoplasmosis and Treponema pallidum. Azithromycin is mainly used for respiratory tract infection, urogenital tract infection, skin soft tissue infection and sexually transmitted diseases caused by sensitive microorganisms.
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