| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
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Pharmaceutical Drug Celecoxib Raw Materials CAS 169590-42-5 Powder Purity Celecoxib
| Product Name | Pharmaceutical Drug Celecoxib Raw Materials CAS 169590-42-5 Powder Purity Celecoxib |
| CAS | 169590-42-5 |
| Molecular formula | C17H14F3N3O2S |
| Molecular Weight | 381.4 |
| Assay | 98% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
|
What is Celecoxib ?Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).Celecoxib |
Celecoxib is used for osteoarthritis, rheumatoid arthritis, acute pain, musculoskeletal pain, painful menstruation,
ankylosing spondylitis, and to reduce the number of colon and rectal polyps in people with familial adenomatous
polyposis.It may also be used in children with juvenile rheumatoid arthritis who are older than two years of age and
weigh more than 10 kg (22 lb).
For postoperative pain, it is more or less equal to ibuprofen. For pain relief, it is similar to paracetamol (acetaminophen)
.And in osteoarthritis, acetaminophen is the first line treatment.In knee and hip osteoarthritis, acetaminophen may be
ineffective.
Application of Celecoxib
Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2
(COX-2) (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). While it was initially hailed as a major therapeutic
advance in treating inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial
anti-inflammatory drugs, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events
. Celecoxib also displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of
its capacity to block COX-2.
Xi'an Henrikang Biotech Co., Ltd., was founded in 2010, And located in Gaoling Industrial Park,Xi'an city,Shannxi
Q:What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from10gs. For other low, price
product,our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier
to us and take the samples. You can send us your product specifications and requests, we will manufacture
the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by
email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your
confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem
caused by us, we will send you free goods for replacement or refund your loss.
Pharmaceutical Drug Celecoxib Raw Materials CAS 169590-42-5 Powder Purity Celecoxib
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