Pharmaceutical Intermediate Celecoxib Powder CAS 169590-42-5 Raw Materials Purity Celecoxib

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: HRK-Celecoxib
• Product Name: Celecoxib Powder
• Appearance: White to off-White Powder
• Test: HPLC
• Mf: C17h14f3n3o2s
• CAS: 169590-42-5
• MW: 381.4
• Active Ingredient: Celecoxib
• Sample: Celecoxib Avaliable
• Certificate: GMP ISO USP Bp
• Assay: 90% Min Celecoxib
• Grade Standard: Feed Grade, Food Grade, Medicine Grade
• Application: Celecoxib Raw Materials
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min Celecoxib
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

                   Pharmaceutical Intermediate Celecoxib Powder CAS 169590-42-5 Raw Materials Purity Celecoxib

Product Name	Pharmaceutical Intermediate Celecoxib Powder CAS 169590-42-5 Raw Materials Purity Celecoxib
CAS	169590-42-5
Molecular formula	C17H14F3N3O2S
Molecular Weight	381.4
Assay	98%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Celecoxib ? Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).Celecoxib Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people .

Fuction of Celecoxib

Celecoxib is used for osteoarthritis, rheumatoid arthritis, acute pain, musculoskeletal pain, painful menstruation,
ankylosing spondylitis, and to reduce the number of colon and rectal polyps in people with familial adenomatous
polyposis.It may also be used in children with juvenile rheumatoid arthritis who are older than two years of age and
weigh more than 10 kg (22 lb).

For postoperative pain, it is more or less equal to ibuprofen. For pain relief, it is similar to paracetamol (acetaminophen)
.And in osteoarthritis, acetaminophen is the first line treatment.In knee and hip osteoarthritis, acetaminophen may be
ineffective.

Application of Celecoxib

Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2
(COX-2) (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). While it was initially hailed as a major therapeutic
advance in treating inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial
anti-inflammatory drugs, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events
. Celecoxib also displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of
its capacity to block COX-2.

 
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Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

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