High Purity Venetoclax CAS 1257044-40-8 Abt-199 Used in Anticancer Drug

• CAS No.: 1257044-40-8
• Formula: C45h50cln7o7s
• EINECS: 820-130-9
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: HRK-Venetoclax
• Colour: Yellow
• Product Name: Venetoclax Powder
• Test: HPLC
• Mf: C45h50cln7o7s
• CAS: 1257044-40-8
• MW: 868.44
• Active Ingredient: Venetoclax
• Sample: Venetoclax Avaliable
• Certificate: GMP ISO USP Bp
• Assay: 90% Min
• Grade Standard: Medicine Grade
• Application: API Raw Materials
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Customized Service: Subassembly
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min Venetoclax
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

  

High Purity Venetoclax CAS No 1257044-40-8 ABT-199 Used in Anticancer Drug

Product Name	Ready Stock High Purity Venetoclax CAS NO 1257044-40-8
CAS	1257044-40-8
Appearance	White crystalline powder
Molecular formula	C45H50ClN7O7S
Molecular Weight	868.44
Assay	98%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Venetoclax? ABT-199 is a white powder, Venetoclax, also known as ABT-199 or GDC0199, ABT-199 is an orally bioavailable, selective small molecule inhibitor of the anti-apoptotic protein Bcl-2, with potential antineoplastic activity. ABT-199 mimics BH3-only proteins, the native ligands of Bcl-2 and apoptosis activators, by binding to the hydrophobic groove of Bcl-2 proteins thereby repressing Bcl-2 activity and restoring apoptotic processes in tumor cells.

Function of Venetoclax

ABT-199 is a small molecule oral drug that treats chronic lymphocytic leukemia (CLL) in those with a specific
chromosomal abnormality.In 2015, the United States Food and Drug Administration (FDA) granted Breakthrough
Therapy Designation to venetoclax for subjects with CLL who have relapsed or have been refractory to previous
treatment and have the 17p deletion genetic mutation.

Application of Venetoclax

ABT-199 is a white powder, Venetoclax, also known as ABT-199 or GDC0199, ABT-199 is an orally bioavailable,
selective small molecule inhibitor of the anti-apoptotic protein Bcl-2, with potential antineoplastic activity. ABT-199
mimics BH3-only proteins, the native ligands of Bcl-2 and apoptosis activators, by binding to the hydrophobic
groove of Bcl-2 proteins thereby repressing Bcl-2 activity and restoring apoptotic processes in tumor cells.

 
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Packaging & Logistics

Package:

1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
 

2. Shipping Advise: 

1. By Express

------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.

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