High Quality API Nepafenac Powder CAS 78281-72-8 Nepafenac Used for Anti-Inflammatory Drug
| Product Name |
High Quality Nepafenac powder CAS 78281-72-8 Best Price |
| CAS |
78281-72-8 |
| Appearance |
Light Yellow Powder |
| Molecular formula |
C15H14N2O2 |
| Molecular Weight |
254.28 |
| Assay |
98% |
| Shelf Life |
24 months when properly stored |
| Storage |
Keep in a cool, dry, dark location |
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What is Nepafenac ?
Nepafenac is a novel ocular non-steroidal antipyretic, analgesic and anti-inflammatory drug (NSAIDs). Nepafenac is used to treat eye pain and inflammation caused by cataract surgery. Compared with traditional NSAIDs, the chemical structure of Nepafenac is favorable for the drug to rapidly penetrate the cornea and distribute at its target site. Therefore, it is helpful to reduce the accumulation of drugs on the surface of the cornea, reduce the occurrence of complications on the surface of the eye, and has the advantages of strong penetration, strong targeting effect and small toxic and side effects.
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Fuction And Application of Nepafenac
Nepafenamine, when administered via the eye, rapidly passes through the cornea and is converted to amifenic acid (an NSAID)
by hydrolases in the eye tissue; Amifenic acid plays an anti-inflammatory and analgesic role by inhibiting prostaglandin H synthetase (cyclooxygenase) and blocking the synthesis of prostaglandin. As is well known, prostaglandins are mediators that cause
inflammation in the eye, leading to breakdown of the blood-aqueous barrier, vasodilation, increased vascular permeability and
leukocyte chemotactic, etc. In addition, prostaglandins can also contract the iris sphincter through non-cholinergic mechanisms,
leading to the constriction of the eyes during and after ophthalmic surgery. When administered via the eye, NSAIDs inhibit the
synthesis of prostaglandins in the iris, ciliary body, and conjunctiva, thereby preventing eye inflammation and reducing associated
pain.
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Packaging & Logistics
Package:
2. Shipping Advise:
1. By Express
------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.
2. By Air
------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.
3. By sea
------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.
1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
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