Powder: | Yes |
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Customized: | Customized |
Certification: | GMP, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | White Powder |
Purity: | >99% |
Samples: |
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Customization: |
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Suppliers with verified business licenses
Product Name
|
Pharmaceutical Intermediate 99% Sunitinib Malate Powder CAS 341031-54-7 Sunitinib Treatment |
Appearance
|
Pale yellow to off-white powder |
Assay
|
99%min, 98.0% --101.0% |
Test
|
HPLC
|
Certificate
|
ISO 9001
|
CAS
|
341031-54-7 |
MF | C26H33FN4O7 |
Storage Temperature |
Cool Dry Place
|
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What is Sunitinib Malate ?Sunitiba Malate is an antineoplastic agent and a potent RTK inhibitor which includes Flk-1 (VEGFR2) as a primary target. It also is a potent, ATP-competitive inhibitor of VEGFR, PDGFR-β and c-Kit (KIT). Sunitiba Malate inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models. Sunitinib Malate is an inhibitor of c-Fms-CSF-1R, Flt-1, Flt-3/Flk-2, Flt-4, PDGFR-α and Ret. |
Sunitinib Malate has very good oral bioavailability, is highly efficacious
in a number of preclinical tumor models, and is well tolerated at efficacious doses.
Sunitinib malate is an inhibitor used in the treatment of advanced renal cell carcinoma
and gastrointestinal stromal tumors.
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