High Quality API Raw Material Cilnidipine Powder CAS 132203-70-4 Used in Hypertensive
Product Name |
Pharmaceutical Intermediate Raw Material Cilnidipine Powder CAS 132203-70-4 Used in Hypertensive Drugs |
CAS |
132203-70-4 |
Appearance |
Light Yellow Powder |
Molecular formula |
C27H28N2O7 |
Molecular Weight |
492.52 |
Assay |
98% |
Shelf Life |
24 months when properly stored |
Storage |
Keep in a cool, dry, dark location |
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What is Cilnidipine ?
Hypertension is a common clinical disease, among which primary hypertension accounts for more than 95%, and its pathogenesis has not been fully elucidated. Hypertension patients have abnormal hemodynamics, accompanied by disorders of fat and sugar metabolism, which can affect the structure and function of the heart, brain, kidney and other important organs, and eventually lead to organ failure. Safe and effective hypotension can reduce the disability rate and mortality of cardiovascular and cerebrovascular diseases. At present, the main drugs for the treatment of hypertension include diuretics, angiotensin converting enzyme inhibitors (ACEI), angiotensin receptor antagonists (ARBs), CCBS and β receptor blockers, among which the application of calcium antagonists has been gradually paid attention to.
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Fuction And Application of Cilnidipine
As a new type of CCB, Sinidipine can act not only on L-type calcium channels on smooth muscle cell membrane to exert
antihypertensive effects, but also on N-type calcium channels on nerve cell membrane to inhibit the release of norepinephrine
and reduce sympathetic nerve activity, with little effect on patients' heart rate. It was found that cilnidipine can effectively reduce
resting blood pressure and the increase of blood pressure under load, and has an inhibitory effect on the activation of sympathetic
nervous system under load.
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Package:
2. Shipping Advise:
1. By Express
------Suitable for under 50kg, Fast:3-4 days. High cost; Door to door service. Easy to pick up the goods.
2. By Air
------Suitable for more than 50 kg, Fast:4-5 days, High cost, airport to airport. professional broker needed.
3. By sea
------Suitable for more than 500kg. Slow: 15-45 days, Low cost. Port to Port, professional broker needed.
1kg per Foil Bag, 10 Bags per carton. 25 kg per Drum. Or Customized Package.
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