Hot Sale 99% Pure Nitrofurantoin Powder CAS 67-20-9 Nitrofurantoin Antibacterial on Sale

• Powder: Yes
• Customized: Customized
• Certification: GMP, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: HRK-Nitrofurantoin
• Product Name: Nitrofurantoin Powder
• Appearance: Light Yellow Crystalline Powder
• Test: HPLC
• Mf: C8h6n4o5
• CAS: 67-20-9
• MW: 238.16
• Active Ingredient: Nitrofurantoin
• Sample: Nitrofurantoin Avaliable
• Certificate: GMP ISO USP Bp
• Assay: 90% Min
• Grade Standard: Feed Grade, Food Grade, Medicine Grade
• Application: Vertinary Raw Materials
• Type of Product: Auxiliaries and Other Medicinal Chemicals
• Storage: Cool Dry Place
• Shelf Life: 2 Years Proper Storage
• Transport Package: 1kg Per Foil Bag, 10 Bags Per Carton. 25 Kg Per Dr
• Specification: 99% min Nitrofurantoin
• Trademark: Henrikang
• Origin: Shaanxi China
• Production Capacity: 500000kg/Year

Product Description

Product Name	Hot sale 99% pure CAS 67-20-9 Nitrofurantoin Powder
CAS	67-20-9
Appearance	Light Yellow Crystalline Powder
Molecular formula	C8H6N4O5
Molecular Weight	238.16
Assay	98%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

What is Nitrofurantoin?   Nitrofurantoin, sold under the trade name Macrobid among others, is an antibiotic used to treat bladder infections.It is not effective for kidney infections. It is taken by mouth. Common side effects include nausea, loss of appetite, diarrhea, and headaches. Rarely numbness, lung problems, or liver problems may occur. It should not be used in people with kidney problems.While it looks like it is generally safe during pregnancy it should not be used near delivery.It works by slowing growth rather than killing bacteria.

Function of Nitrofurantoin

The mechanism of action of nitrofurantoin is unique and complex. The drug works by damaging bacterial
DNA, since its reduced form is highly reactive.This is made possible by the rapid reduction of nitrofurantoin
inside the bacterial cell by flavoproteins (nitrofuran reductase) to multiple reactive intermediates that
attack ribosomal proteins, DNA,respiration, pyruvate metabolism and other macromolecules within the cell
. Nitrofurantoin exerts greater effects on bacterial cells than mammalian cells because bacterial cells
activate the drug more rapidly. It is not known which of the actions of nitrofurantoin is primarily responsible
for its bactericidal activity. The broad mechanism of action for this drug likely is responsible for the low
development of resistance to its effects, as the drug affects many different processes important to the
bacterial cell.

Application of Nitrofurantoin

Nitrofurantoin has been available for the treatment of urinary tract infections (UTIs) since 1953. Its current
uses include the treatment of uncomplicated UTIs and prophylaxis against UTIs in people prone to
recurrent UTIs.

Increasing bacterial antibiotic resistance to other commonly used agents, such as fluoroquinolones and
trimethoprim/sulfamethoxazole, has led to increased interest in using nitrofurantoin.Several trials
comparing nitrofurantoin to other commonly used agents have shown this drug results in similar cure
rates for uncomplicated UTIs.The efficacy of nitrofurantoin in treating UTIs combined with a low rate
of bacterial resistance to this agent makes it one of the first-line agents for treating uncomplicated UTIs
as recommended by the Infectious Diseases Society of America and the European Society for
Microbiology and Infectious Diseases.Nitrofurantoin is not recommended for the treatment
ofpyelonephritis,prostatitis and intra-abdominal abscess,because of extremely poor tissue penetration
and low blood levels.

It is used in the treatment of infections caused by these organisms.